The Link Between Asbestos Exposure and Smoking

It is common knowledge that smoking is hazardous to one’s health. Additionally, many people know that exposure to asbestos is very dangerous and can lead to the development of the disease mesothelioma. What many people do not know, however, is that when smoking and asbestos exposure are combined, both of the harmful elements work together to create a much higher risk for the development of mesothelioma, or other types of cancers.

Cigarettes have many harmful chemicals that break down the lungs and can be leading causes in cancer. Asbestos exposure also exposes the lung to harmful chemicals that weaken your body’s defenses against cancers and other lung problems. Studies have found that cigarette smokers have a four to eleven times greater chance of getting lung cancer than non-smokers. If a person is a heavy smoker, than the number goes up to twenty-seven times as likely. Adding a heavy smoker to asbestos exposure sends the probabilities for lung cancer skyrocketing. In fact, heavy smokers with a history of asbestos exposure have a 50 to 90 times greater chance of having lung cancer. Needless to say, heavy smoking and large amounts of asbestos exposure will almost certainly lead to lung cancer.

Smoking causes chronic obstructive pulmonary disease (COPD). People who smoke and have been exposed to asbestos have higher occurrences of COPD than people who have not been exposed to asbestos. Some of the terrible effects of COPD are the inflammation and eventual destruction of small airways in the lung tissue. Once these tissues have been destroys, some people can be completely debilitated.

Studies have shown that people who quit smoking, but still had asbestos exposure are less likely to have lung cancer than those people who continue to smoke. Some say that COPD can be reversed the longer time is spent without smoking. Additionally, people who are able to quit smoking often feel healthier over time and significantly increase their life expectancy. Even though any amount of smoking or asbestos exposure can lead to lung cancer, the sooner one quits, the better off he or she will be.

Asbestos exposure is very harmful for anyone. However if you know that you have been exposed to asbestos, and continue to smoke, you are playing with fate. The sooner someone stops smoking, the sooner his or her lungs can begin to heal. Mesothelioma and other cancers are very serious diseases that often end in death. In order to stay alive for loved ones, smokers should quit immediately.

Mesothelioma treatments: What are my options?

Clinical research to treat malignant mesothelioma is very active and although no treatment has yet proved entirely successful, there exist a range of treatments available to individuals diagnosed with the disease.  There are three types of standard treatments used to treat malignant mesothelioma which include: surgery, radiation therapy, and chemotherapy. 

Surgery
Surgery for malignant mesothelioma is divided into a number of sub-classes, which are specially designed to limit the disease for individuals with particular strains of the disease.

Extrapleural pneumonectomy is a severe form of surgery in which the entire lung and a portion of the lining of the chest, the diaphragm, and some or the entire sac which surrounds the heart is removed.

Wide local excision is a form of surgery which targets and removes the cancer and a limited amount of the healthy tissue surrounding the cancerous region. 

Pleurectomy and decortication removes part of the covering of the lungs, as well as the lining of the chest and portions of the outside covering of the lungs.

The surgical procedure pleurodesis is a distinct technique insofar as it employs a blend of chemicals and/or drugs to create an intentional scar between the layers of the pleura.  Post surgery, the space created by the scar must be drained, using either a catheter or chest tube, and is then filled with a chemical which inhibits the accumulation of fluid in the pleura cavity.

Radiation
The second primary medical technique used to fight the development of malignant mesothelioma is radiation.  Radiation therapy, as applied to malignant mesothelioma uses the same basic technology as other forms of medical radiation insofar as the technique employs high energy x-rays to kill cancer cells.  The process is divided into two broad categories:

External radiation therapy is a technique in which a machine sends radiation in a targeted stream at a certain portion of the body, and in so doing it kills the cancerous cells in its purview.

Internal radiation therapy, by contrast, uses not an external machine, but rather needles, seeds and catheters to place radioactive substance directly on or near the cancer.  While the precise method of implementation will of course depend upon the type and stage of the illness,  what is constant within this category is that the goal is to get the radiation placed directly onto the cancerous area and in so doing provide a more concentrated and directed dosage.

Chemotherapy
The third standard malignant mesothelioma treatment is Chemotherapy.  Chemotherapy uses drugs which target cancer cells and stop them from dividing and thus prevent their growth. 
In systemic chemotherapy, the drug can be taken by mouth or injected, but either way the goal is to have it reach cancer cells by means of the body’s own blood circulation system.  In regional chemotherapy, the drug is placed directly onto the target area.  And finally, combination chemotherapy involves the use of two or more anticancer drugs which can be administered either orally or through injection. 

Malignant mesothelioma is a difficult disease for anyone to bear, however, educating oneself as to the options available is an important step for making the process more manageable.

Who is at Risk for Mesothelioma?

Mesothelioma, the deadly disease which has topped news headlines for the last decade, is contracted through exposure to airborne fibers of asbestos.  Sadly, the under-regulation of asbestos usage in years past, and arguably still today, exposed millions to airborne fibers and as a result thousands contracted the disease. 

It can be safely said that almost everyone in the world has been exposed to asbestos in varying degrees. Because of the unique nature of the disease, even those who have suffered only minimal exposure are at risk of contracting the disease.  In effect, virtually everyone has some risk of contracting Mesothelioma. 

But this sort of statement perhaps oversteps the bounds of rationality.  While it is certainly true that individuals who have been exposed to small amounts of asbestos for relatively short periods of time have contracted the disease, this is a rarity rather than a regularity.  In fact, the vast majority of Mesothelioma cases involve individuals who were exposed to airborne asbestos fibers for intense and extended periods of time.

The industries most in danger of prolonged exposure and thus of contraction are shipbuilding trades, asbestos mining and milling, textile manufacturing, insulation work in construction, and brake repair personnel. There are, however, some other minor factors which can affect the likelihood of contracting the disease.  Among these is radiation exposure.  There have been causes in which individuals who were exposed to radiation have subsequently displayed signs of and ultimately contracted mesothelioma.  However, empirical studies to attempt to verify this correlation have not proven out this claim very strongly. 

Another more certain cause of the disease was the taking of the Polio vaccine between 1955 and 1963.  Some batches of this vaccine were contaminated with Simian Virus 40 which has been detected in a host of rare cancers including Mesothelioma.

Those involved in construction or who lived in homes in the Cappadocian region of Turkey are also particularly at risk.  In this region, homebuilders used Erionite, which is a type of zeolite silica stone.  Exposure to the fibrous strands of this building material have led to an annual death rate of roughly 1% of the population which dies of mesothelioma each year in Turkey.  

One of the most influential factors affecting Mesothelioma contraction is genetics.  Some individuals who have been exposed to long periods and high quantities of asbestos have not contracted the disease.  As a result, doctors have concluded that genetics play a major role in determining whether or not patients contract the disease.  Unfortunately, the gene variability which offers some resistance to the disease also means that some are particularly vulnerable to asbestos exposure.

Mesothelioma

Tragically the word mesothelioma is becoming more and more well known, the mere mention of it striking fear into all of us for we know that it is associated with death.  Asbestos is the reaper, mesothelioma its hand maiden. 

Asbestos, the wonder product of the fifties is now recognized as an enemy of the twentieth century. A ruthless enemy which will kill more people than the war.  Men, women and children will fall victim to its prey, innocents who have at some time in their lives inhaled asbestos dust. 

Most of us have been in contact with products containing asbestos in our life times.  We sat in asbestos class rooms, stood beside our fathers as they cut asbestos fencing, pulled up old linoleum with asbestos clogged to the back of it.  Visited the local tip where broken sheets of it lay open to the wind.

Records show that there are a higher number of people afflicted with asbestosis and mesothelioma who have directly worked in asbestos mines, ship yards and companies making products from asbestos; however there are a large number of people afflicted, who have never worked in these industries.  Their contact with asbestos, due to the dust brought home on their husband’s clothes or from the asbestos tailings placed around mine houses and town perimeters.  But the tragedy does not end there, children innocently playing in their own back yards played amongst the asbestos tailings as children elsewhere play in the sand.  They had no way of knowing that their sand was asbestos blue.  A good bath at the end of the day may have removed the dust from the skin but the dust in the lungs remained and would lay dormant for many years before claiming its deadly legacy.

Without warning, a healthy individual suddenly becomes short of breath, x-rays reveal fluid on the lungs and the night mare begins.  Questions are asked and you answer, Yes, I was exposed to asbestos dust but I was only in the town for a few short months and that was over 40 years ago.  How can this be? This is the most perplexing thing about mesothelioma.  Why is there such a long period of time between inhalation of asbestos dust and onset of the disease?  What triggers a strong healthy body to suddenly succumb to it?  What can we do to prevent this from happening?

Blood tests are now available to determine whether mesothelioma is present in the body, before a person is aware of any symptoms.  This is an amazing breakthrough and perhaps the first step towards curing the disease before it becomes terminal.  Recently mesothelioma was cured in a mouse and attempts to give it back to the mouse were unsuccessful.  This too is exciting stuff and holds a glimmer of hope for us all. 

I have witnessed first hand the devastation of mesothelioma. My husband was a strong and virile man who rarely had a sick day in his life.  Suddenly at the age of 52 he became short of breath and was subsequently diagnosed with pleural mesothelioma.  He had lived in the asbestos mining town of Wittenoom in Western Australia for a few short months at the age of seven.  The asbestos dust he inhaled then, took forty five years to become lethal.  I still find this hard to believe.

Despite his prognosis of three to nine months, Brian survived for two years.  He was 54 years old when he died.